The formulation for the stabilization of sodium ascorbate dispersed in polymeric matrix of carbômero 934p for removal of residual oxygen of dental enamel newly cleared

摘要

The formulation for the stabilization of sodium ascorbate dispersed in polymeric matrix of carbômero 934p for removal of residual oxygen of dental enamel newly cleared.This invention relates to the development of a hydrogel formulation of carbopol 934p 3,75%, sodium ascorbate, 20%, to be used in the field of dentistry.With chemical stability sufficient for their marketing, since due to oxidant characteristics, up to the present there is no product commercially.The sodium ascorbate should be applied on the tooth surfaces after treatment of tooth whitening.The purpose is to restore the ability of dental enamel to receive adhesive restorations.Have been developed hidrogéis preparations containing sodium ascorbate (10 and 20% (w / W) of carbopol gel 934p (2.5 and 3.75% (w / W).Determination of sodium ascorbate was measured by iodometric titration in 1, 7, 14, 21ºe 30 days,And its presence was greater for the formulations containing 20% of this component to 30 days.In addition, the formulations of sodium ascorbate 10 and 20% and 3.75% of carbopol 934p were titrated at intervals of 30 days to 180 days.The formulation containing 20% of sodium ascorbate in 3.75% of carbopol gel 934p resulted in better stability, higher than other developed, showing the feasibility of commercial production.