首页>
外国专利>
ab peptide immunogen construct, its use, composition comprising it, alzheimer dementia prevention and immunotherapy peptide vaccine and antibody.
ab peptide immunogen construct, its use, composition comprising it, alzheimer dementia prevention and immunotherapy peptide vaccine and antibody.
展开▼
机译:ab肽免疫原构建体,其用途,包含它的组合物,预防老年痴呆和免疫疗法的肽疫苗和抗体。
展开▼
页面导航
摘要
著录项
相似文献
摘要
abstract the present disclosure is directed to individual peptide immunogen constructs, peptide compositions comprising these a peptide immunogen constructs and mixtures thereof, pharmaceutical compositions including vaccine formulations comprising these a peptide immunogen constructs, with the individual peptide immunogen constructs having the n-terminus of the aß peptide as the b cell (b) epitopes linked through spacer residue (s) to heterologous t helper cell (th) epitopes derived from pathogen proteins that act together to stimulate the generation of highly specific antibodies directed against the n-terminus of the aß peptide offering protective immune responses to patients at risk for or with alzheimer's disease. alzheimer dementia prevention and immunotherapy peptide vaccine The present invention relates to individual α-immunogen peptide constructs, peptide compositions comprising these α-immunogen peptide constructs and mixtures thereof, pharmaceutical compositions including vaccine formulations comprising these α-immunogen peptide constructs, with the individual α-immunogen peptide constructs having the β-peptide n-terminus, such as cell b (b) epitopes linked via heterologous t helper cell epitope (th) spacer residue (s) pathogenic protein derivatives that act together to stimulate the production of highly specific antibodies directed against the ß-peptide n-terminal offering protective immune responses to patients at risk for or with Alzheimer's disease.
展开▼