The production process of polymeric nanoparticles containing the compound disseleneto of difenila by the method of dessolvatau00e7u00e3o

摘要

? The production process of polymeric nanoparticles containing the compound disseleneto of difenila by the method of dessolvatau00e7u00e3o? .The present invention includes the production of polymeric nanoparticles containing disseleneto of difenila (pdsd) coated with the polymer of natural bovine serum albumin (ASB)By the method of dessolvatau00e7u00e3o as an alternative to the carried drug.This invention provides the development of nanoparticles with controlled size and high capacity of encapsulation of the pdsd,Aiming at the improvement of the physical and chemical properties of the compound with respect to its solubility.Stability in physiological media and kinetics of release and sustained direcionu00e1vel locations of desired action, acting in this way, in an improvement of its pharmacokinetics and bioavailability.The polymeric nanoparticles developed in this invention are promising, since the pdsd presents a wide range of biological and pharmacological activities.