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polycomplex gel for the treatment of intestinal / digestive tract diseases

机译:高分子复合凝胶治疗肠/消化道疾病

摘要

The polycomplex gel for the treatment of intestinal / digestive tract diseases The invention relates to the chemical and pharmaceutical industry and consists of a rectal gel substance for the treatment of intestinal / digestive tract diseases including non-specific ulcerative colitis, disease. crohn's, fistulas, etc., and also complications during the course of treatment of said diseases. The invention provides an antimicrobial and antiprotozoal effect and has good penetration capabilities. The technical result achieved by carrying out the claimed invention is to increase the treatment effectiveness of noninfectious inflammatory bowel / digestive tract diseases and shorten the duration of treatment. said technical result is achieved by means of a poly complex gel for the treatment of intestinal / digestive tract diseases, said gel containing metronidazole and thymogen as the active substances and containing the following auxiliary substances, in composition and in the ratio between components. then in grams, with a total gel mass of 150 grams: metronidazole: 0,1 to 2 g; thymogen: 0.001 to 0.05 g; carbopol: 0.2 to 1.0 g; propylene glycol: 8.0 to 11.0 g; edta disodium salt: 0.001 to 0.08 g; propyl parahydroxybenzoate: 0.015 to 0.04 g; methyl parahydroxybenzoate: 0.035 to 0.08g; sodium hydroxide: an amount sufficient to produce the required ph; distilled water: the rest.
机译:用于治疗肠/消化道疾病的多复合凝胶技术领域本发明涉及化学和制药工业,并且由用于治疗包括非特异性溃疡性结肠炎,疾病的肠/消化道疾病的直肠凝胶物质组成。克罗恩病,瘘管等,以及在所述疾病的治疗过程中的并发症。本发明提供了抗微生物和抗原生动物作用,并具有良好的渗透能力。通过实施要求保护的发明而获得的技术结果是提高非感染性炎症性肠/消化道疾病的治疗效果并缩短治疗时间。所述技术结果是通过用于治疗肠/消化道疾病的多复合凝胶获得的,所述凝胶含有甲硝唑和胸腺素作为活性物质,并且含有以下辅助物质,其组成和成分之间的比例。然后以克计,总凝胶质量为150克:甲硝唑:0.1至2克;胸腺素:0.001至0.05 g;卡波普尔:0.2至1.0克;丙二醇:8.0至11.0 g; EDTA二钠盐:0.001至0.08 g;对羟基苯甲酸丙酯:0.015至0.04 g;对羟基苯甲酸甲酯:0.035至0.08g;氢氧化钠:足以产生所需酸碱度的量;蒸馏水:其余。

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