首页> 外国专利> compound, medicament, methods for reducing retinol binding protein 4 and for prophylaxis or treatment of macular degeneration and / or a disease, and use of a compound.

compound, medicament, methods for reducing retinol binding protein 4 and for prophylaxis or treatment of macular degeneration and / or a disease, and use of a compound.

机译:化合物,药物,减少视黄醇结合蛋白4以及预防或治疗黄斑变性和/或疾病的方法,以及该化合物的用途。

摘要

It is a heterocyclic compound that has an excellent rbp4 reducing effect and is useful as a preventive or therapeutic drug for diseases or symptoms mediated by an increase in rbp4 or rbp4-supplied retinol. a compound represented by the formula (i): [the symbols in the formula are as mentioned in the description.] or a salt of said compound has an excellent rbp4 reducing effect and is useful as a preventive or therapeutic drug for diseases or symptoms mediated by an increase in rbp4 or retinol supplied by rbp4.
机译:它是一种杂环化合物,具有出色的rbp4还原作用,可用作预防或治疗药物,用于治疗因rbp4或rbp4提供的视黄醇增加而介导的疾病或症状。式(i)表示的化合物:[式中的符号如说明书中所述。]或该化合物的盐具有优异的rbp4还原作用,可用作预防或治疗介导的疾病或症状的药物。通过增加rbp4或rbp4提供的视黄醇。

著录项

  • 公开/公告号BR112017007138A2

    专利类型

  • 公开/公告日2017-12-26

    原文格式PDF

  • 申请/专利权人 TAKEDA PHARMACEUTICAL COMPANY LIMITED;

    申请/专利号BR20171107138

  • 申请日2015-10-22

  • 分类号A61K31/505;A61K31/415;A61K31/421;A61K31/4418;A61P1;A61P1/12;A61P1/16;A61P1/18;A61P3;A61P3/04;A61P3/06;A61P5/50;A61P7;A61P9/04;A61P9/10;A61P9/12;A61P11;A61P13/12;A61P15/08;A61P19/02;A61P19/10;A61P21;A61P21/04;A61P25/02;A61P25/16;A61P25/22;A61P25/28;A61P27/02;A61P27/06;A61P29;A61P35;A61P35/02;A61P43;C07D213/65;C07D231/12;C07D231/22;C07D239/34;C07D263/38;C07K14/47;C12N15/09;

  • 国家 BR

  • 入库时间 2022-08-21 12:53:49

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