The invention relates to chimeric or humanized anti-cd303 antibodies to nucleic acids encoding the heavy and light chains of these antibodies, expression vectors, host cells, transgenic non-human animals or transgenic plants expressing said antibodies, as well as their uses. in treating or preventing blast plasmocytoid dendritic cell (bpdcn) neoplasms or inflammatory diseases, in particular autoimmune diseases, involving plasmocytoid dendritic cells.
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