nut midline carcinoma treatment

摘要

Disclosed herein is a method of treating midline carcinoma (nmc) derived from the testicular nuclear protein (nut) in an individual in need thereof, comprising administering an effective amount of a bromodomain inhibitor, wherein the effective amount can be determined according to cd11b expression levels, which monitors the responsiveness of nmc to the bromodomain inhibitor. Also disclosed herein is a method for determining a bromodomain inhibitor treatment regimen in an individual suffering from nmc.