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peptides and peptide combinations for use in immunotherapy against ovarian epithelial cancer and other cancers

机译:肽和肽组合用于卵巢上皮癌和其他癌症的免疫治疗

摘要

The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapy methods. more specifically, the present invention relates to cancer immunotherapy. The present invention also relates to peptide epitopes obtained from tumor-associated t-cells, alone or in combination with other tumor-associated peptides, which may, for example, act as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses or stimulate ex vivo t cells, which are then transferred to patients. Peptides, whether bound to major histocompatibility complex (mhc) molecules or peptides as such, can also be targets for antibodies, soluble t-cell receptors and other ligand molecules.
机译:本发明涉及用于免疫治疗方法的肽,蛋白质,核酸和细胞。更具体地,本发明涉及癌症免疫疗法。本发明还涉及单独地或与其他肿瘤相关肽组合地从肿瘤相关t细胞获得的肽表位,其例如可以用作刺激抗肿瘤免疫应答或免疫应答的疫苗组合物的活性药物成分。刺激离体t细胞,然后将其转移给患者。肽,无论是与主要的组织相容性复合物(mhc)分子还是与肽结合,都可以成为抗体,可溶性t细胞受体和其他配体分子的靶标。

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