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readjustment of biological pathways of defense against and repair of damage caused by human aging

机译:防御和修复人类衰老造成的生物学途径的重新调整

摘要

Compositions for resolving one or more of the aging effects are described. the compositions comprise a first component comprising repair system activator (s) such as nicotinamide adenine dinucleotide (nad +), nicotinamide mononucleotide (nmn), nicotinamide riboside (nr), nicotinic acid mononucleotide adenine (namn), nicotinic acid adenine (naad) ), nicotinic riboside acid (nar), 1-methylnicotinamide (mnm), adenosine monophosphate (camp) and combinations thereof; a second component comprising methyl donor (s) such as s-5'-adenosyl-1-methionine (sam), methionine, betaine, choline, folate, vitamin b12, or combinations thereof; and a third component comprising antioxidant defense activators such as h2o2, n2s, nash, na2s, and various others, including combinations thereof. Methods of administering the disclosed compositions or separate formulations of repair system activator, methyl donors, and antioxidant defense activators are also described.
机译:描述了用于解决一种或多种老化作用的组合物。所述组合物包含第一组分,所述第一组分包含修复系统活化剂,例如烟酰胺腺嘌呤二核苷酸(nad +),烟酰胺单核苷酸(nmn),烟酰胺核糖苷(nr),烟酸单核苷酸腺嘌呤(namn),烟酸腺嘌呤(naad)。 ,烟碱核糖苷酸(nar),1-甲基烟酰胺(mnm),单磷酸腺苷(camp)及其组合;第二组分,其包含甲基供体,例如s-5′-腺苷-1-蛋氨酸(sam),蛋氨酸,甜菜碱,胆碱,叶酸,维生素b12或其组合;以及第三组分,其包含抗氧化剂防御活化剂,例如h 2 O 2,n 2s,nash,na 2s以及各种其他物质,包括其组合。还描述了施用修复系统活化剂,甲基供体和抗氧化剂防御活化剂的公开的组合物或单独制剂的方法。

著录项

  • 公开/公告号BR112018007153A2

    专利类型

  • 公开/公告日2018-11-06

    原文格式PDF

  • 申请/专利权人 JOEL HUIZENGA;

    申请/专利号BR20181107153

  • 发明设计人 JOEL HUIZENGA;

    申请日2016-10-03

  • 分类号A61P39;A23L33/13;A23L33/175;A61K36/48;

  • 国家 BR

  • 入库时间 2022-08-21 12:53:32

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