infectious arenavirus viral vector, pharmaceutical composition, immunogenic composition, vaccine, method for treating or preventing hepatitis b virus infection in a patient, use of a viral vector, isolated nucleic acid, replication-deficient infectious arenavirus viral vector and method for its generation

摘要

The present invention relates to immunotherapies for hepatitis b virus infections. The present patent application provides genetically modified arenaviral vectors suitable as vaccines for the prevention and treatment of hepatitis b virus infections. In addition, pharmaceutical compositions and methods for treating hepatitis B virus infections are also provided. specifically, pharmaceutical compositions, vaccines and methods for treating hepatitis b virus infection are provided herein.