COMPOSITION UNDERSTANDING NEISSERIA MENINGITIDIS SERB GROUP EXTERNAL MEMBRANE VESICULES AND AN INORGANIC COMPONENT AND USE OF THE SAME

摘要

"Outer membrane vesicle (omv) vaccine comprising neisseria meningitidis serum group b outer membrane proteins". a composition comprising (a) neisseria meningitidis serum group b outer membrane vesicles (omvs) and (b) a selected immunogenic component or among other neisseria proteins or immunogenic fragments thereof. component (b) preferably includes a protein from a strain other than that from which the omvs of component (a) are derived. omvs are preferably obtained by deoxycholate extraction. optionally, the composition may also comprise a protective antigen against other pathogens.