The pH sensitive hydrogel porous polymer, and method for preparing the same

摘要

Methods for treatment of a disease or disorder, deformation of a patient for human or veterinary, and for the preparation of a polymer of environmentally sensitive hydrogel and hydrogel.Hidrogu00e9is that expand volumetricamente in response to changes in its environment (e.g., a change in pH or temperature) and their methods of manufacture and use.Generally, the hidrogu00e9is are prepared by forming a mixture of the reaction liquid which contains (a) monomer (s) and / or polymer (s),At least a part (s) of which are sensitive to environmental changes (for example, changes in pH or temperature), (b) a reticulador and (c) a polymerization initiator.If desired, a porosigu00eanio can be incorporated in the mixture of liquid reaction to create pores. After the hydrogel is formed, the porosigu00eanio is removed to create pores in the hydrogel.The hydrogel can also be treated to make him take a volume not expanded as it remains until a change in its environment make him expand.These hidrogu00e9is can be prepared in many forms including granules, filaments and particles.These hidrogu00e9is biomedical uses include applications in which the hydrogel is implanted in the body of a patient and an environmental condition at the implantation site causes the hydrogel expands in situ.