首页> 外国专利> USE OF AGONISTS OF THE COUPLED RECEIVER TO PROTEIN G, BUT, IN THE TREATMENT OF METABOLIC SYNDROME, ITS COMPONENTS AND THEIR COMPLICATIONS

USE OF AGONISTS OF THE COUPLED RECEIVER TO PROTEIN G, BUT, IN THE TREATMENT OF METABOLIC SYNDROME, ITS COMPONENTS AND THEIR COMPLICATIONS

机译:在蛋白质代谢综合征,其成分和其并发症的治疗中使用蛋白G受体偶联受体的激动剂

摘要

g protein coupled receptor agonists, but in the treatment of metabolic syndrome, its components and its complications. The present invention is characterized by the use of g protein-coupled receptor agonists, but as a mechanism of control, prevention and treatment of body levels of triglycerides, cholesterol and glucose, as well as arterial hypertension and possible increase in body weight, characteristic of the metabolic syndrome and its complications. Another feature of the invention is the use of g-protein coupled receptor agonists, but including the angiotensin- (1-7) peptide and its analogs, agonists, peptides or non-peptides as modulators of insulin resistance and intolerance pictures. glucose and the prevention and treatment of related changes. The invention claims the use of g-protein coupled receptor agonists, but formulated with pharmaceutically and pharmacologically acceptable excipients or carriers, and g-protein coupled receptor agonists, but including the angiotensin- (1-7) peptide and analogs thereof , agonists, peptides or non-peptides as modulators of the metabolic syndrome, its diseases and their complications.
机译:g蛋白偶联受体激动剂,但在代谢综合症的治疗中,其成分及其并发症。本发明的特征在于使用g蛋白偶联的受体激动剂,但是作为控制,预防和治疗机体甘油三酸酯,胆固醇和葡萄糖水平以及动脉高血压以及体重可能增加的机制,这是本发明的特征。代谢综合征及其并发症。本发明的另一个特征是使用g蛋白偶联受体激动剂,但包括血管紧张素-(1-7)肽及其类似物,激动剂,肽或非肽作为胰岛素抗性和不耐受性图片的调节剂。血糖与防治有关的变化。本发明要求使用g蛋白偶联受体激动剂,但与药学和药理学上可接受的赋形剂或载体,以及g蛋白偶联受体激动剂一起配制,但包括血管紧张素-(1-7)肽及其类似物,激动剂,肽。或非肽作为代谢综合征,其疾病及其并发症的调节剂。

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