Method for determining if a cancer in a patient is resistant to treatment with an antimitotic agent, Method for treating a cancer patient that is resistant to the antimitotic agent, and Method of treatment

摘要

Methods and compositions are provided to determine if a cancer is resistant to treatment with anti-mitotic agents, including treatment with T-DM1. The methods relate to determining if the ABCC3 gene is amplified and/or overexpressed in the cancer.