a composition comprising 9 2 bis (pivaloyloxy) methyl phosphono methoxy ethyl adenine, tablet or capsule and method

摘要

patent: "pharmaceutical formulations". The invention provides compositions comprising the 9- [2 - [[bis [(pivaloyloxy) methyl] phosphono] methoxy] ethyl] adenine nucleotide analog and an alkaline excipient with or without 1-carnitine-1-tartrate. The compositions are more stable than those previously described. The invention also provides methods for producing the compositions and their intermediates.