首页> 外国专利> Compounds with amide groups of biphenyl ethers modified Derivatives of N - ((2 - (cyclohexyloxy or 2H - piran - 2 - iloxi) - 3 '- fluoro 11 '- biphenyl - 2 - il) - ethyl) - acetamide and 2 - oxo - 2H - cromen 3il - substituted acetamide; compositions and pharmacological inhibitors of hsp90, Hsp70 inducers, useful for treating Neurological Disorders,Associated with diabetic complications such as neuropathy, nephropathy, retinopathy and Vascular Disease. Modified as inhibitors of Hsp90 and Hsp70 inducers (DIV no 3276 - 16)

Compounds with amide groups of biphenyl ethers modified Derivatives of N - ((2 - (cyclohexyloxy or 2H - piran - 2 - iloxi) - 3 '- fluoro 11 '- biphenyl - 2 - il) - ethyl) - acetamide and 2 - oxo - 2H - cromen 3il - substituted acetamide; compositions and pharmacological inhibitors of hsp90, Hsp70 inducers, useful for treating Neurological Disorders,Associated with diabetic complications such as neuropathy, nephropathy, retinopathy and Vascular Disease. Modified as inhibitors of Hsp90 and Hsp70 inducers (DIV no 3276 - 16)

机译:带有联苯醚酰胺基的化合物修饰了N-((2-(环己氧基或2H-piran-2-iloxi)-3'-氟[11'-联苯]-2-il)-乙基)-乙酰胺和2的衍生物-氧代-2H-cromen 3il-取代的乙酰胺; hsp90,Hsp70诱导剂的组合物和药理抑制剂,可用于治疗与糖尿病并发症(如神经病,肾病,视网膜病和血管疾病)相关的神经系统疾病。修饰为Hsp90和Hsp70诱导剂的抑制剂(DIV No 3276-16)

摘要

Compounds derived from N - ((2 - (cyclohexyloxy or 2H - piran - 2 - iloxi) - 3 '- fluoro [1,1' - biphenyl] - 2 - il) - ethyl) - acetamide and 2 - oxo - 2H - cromen 3il - acetamide, substitutedInhibitors of Hsp90 and Hsp70 inducers; Pharmaceutical Composition and use for treating Neurological Disorders, diabetes, and cancer, among others (Divisional Application 201603276).
机译:衍生自N-(((2--(环己氧基或2H-piran-2-iloxi)-3'-氟[1,1'-联苯]-2-il)-乙基)-乙酰胺)-乙酰胺和2-氧代-2H-的化合物cromen 3il-乙酰胺,Hsp90和Hsp70诱导剂的取代抑制剂;药物组合物及其在治疗神经系统疾病,糖尿病和癌症等方面的用途(分案申请201603276)。

著录项

  • 公开/公告号CL2018002367A1

    专利类型

  • 公开/公告日2018-10-12

    原文格式PDF

  • 申请/专利权人 THE UNIVERSITY OF KANSAS;

    申请/专利号CL20180002367

  • 申请日2018-08-17

  • 分类号C07D307/14;C07D309/10;A61K31/341;A61K31/35;A61P13/12;A61P25/02;A61P25/28;A61P27/02;A61P3/10;A61P35;A61P9;A61P9/10;

  • 国家 CL

  • 入库时间 2022-08-21 12:53:11

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