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Antibacterial agent for the treatment of infectious diseases of bacterial origin

机译:用于治疗细菌源性传染病的抗菌剂

摘要

The invention relates to medicine, namely to the antimicrobial agent for the treatment of infectious bacterial diseases including hospital infections and drug-resistant TB which represents the ion nanostructured complex (INSC) synthesized from carbohydrates proteins and/or polypeptides (albumins, interleukins, interferons, signaling proteins, etc), which are to enhance the antimicrobial activity in vivo, by activating immune cells that contain at least one terminal amino acid such as Phe, Ala, Val, Ala, Leu, Ile, and others with electron-donor functional groups, iodine and halides of the alkali and alkaline earth elements in the fourth stage at a certain ionic strength; an antibacterial agent increases: the susceptibility of bacteria, including antibiotic-resistant, to antibiotics; activity of monocytes and macrophages; efficiency of antibiotic treatment of hospital infections and drug-resistant TB; it also has antiviral activity, stimulates hematopoietic function of bone marrow; has an antitumor effect and radioprotective properties; in acceptable concentrations of components can be used as non-pharmaceutical agent (BAFS or parapharmaceutical); is presented in the pharmacological form suitable for parenteral, oral, external, or other application. INSC has the formula [{(Ln (MeI3) +) y [Me (Lm) I] + x} (Cl-) y + x + k] with M = 30-300 kDa.
机译:本发明涉及药物,即涉及用于治疗包括医院感染和耐药性TB在内的传染性细菌疾病的抗微生物剂,其代表由碳水化合物蛋白和/或多肽(白蛋白,白介素,干扰素,信号蛋白等),通过激活包含至少一个末端氨基酸的免疫细胞(例如Phe,Ala,Val,Ala,Leu,Ile和其他具有电子供体功能基团的免疫细胞)来增强体内的抗微生物活性第四阶段的碱金属和碱土金属元素中的碘和卤化物具有一定的离子强度;抗菌剂增加:细菌(包括抗药性)对抗生素的敏感性;单核细胞和巨噬细胞的活性;抗生素治疗医院感染和耐药结核病的效率;它还具有抗病毒活性,刺激骨髓的造血功能。具有抗肿瘤作用和辐射防护特性;可接受浓度的组分可用作非药物制剂(BAFS或辅助药物);以适合于肠胃外,口服,外用或其他应用的药理形式存在。 INSC具有公式[{(Ln(MeI3)+)y [Me(Lm)I] + x}(Cl-)y + x + k],M = 30-300 kDa。

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