METHOD OF TREATMENT OF MALIGNANT WORK OVARIAN TUMOR (MRTO) / MICRO-CELLULAR CANCER OF OVARIES OF HYPERCALCEMIC TYPE (SCCOHT) WITH THE HELP OF EZH2 INHIBITOR

摘要

The present invention provides a method for treating a malignant rhabdoid tumor in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of an enhancer inhibitor of the zeste 2 homolog (EZH2). In certain embodiments of this method, the malignant rhabdoid tumor is a small-cell hypercalcemic-type ovarian cancer (SCCOHT) and the EZH2 inhibitor is a tasemetostat (also known as Tazemetostat).