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NATURAL HILLS AND ILC3 CELLS AND THEIR APPLICATION

机译:天然山丘和ILC3细胞及其应用

摘要

In the framework of the present invention, methods are provided for producing natural killer (NK) and / or ILC3 cells using a three-step method of increasing the number and differentiation using a medium containing factors that mobilize stem cells. Also in the framework of the present invention, methods are provided for suppressing the proliferation of tumor cells using NK cells and / or ILC3 cells and populations of NK cells and / or ILC3 cells obtained by the three-step methods described herein, as well as methods for treating individuals with a malignant tumor or viral infection, including the administration to an individual with a malignant tumor or viral infection of NK cells and / or ILC3 cells and populations of NK cells and / or ILC3 cells obtained by three-step methods, op sleigh herein.
机译:在本发明的框架中,提供了使用三步法产生自然杀伤(NK)和/或ILC3细胞的方法,所述方法使用含有动员干细胞因子的培养基来增加数量和分化。同样在本发明的框架中,提供了使用NK细胞和/或ILC3细胞以及通过本文所述的三步法获得的NK细胞和/或ILC3细胞的群体抑制肿瘤细胞增殖的方法,以及治疗具有恶性肿瘤或病毒感染的个体的方法,包括给予具有三步法获得的NK细胞和/或ILC3细胞以及NK细胞和/或ILC3细胞群体的恶性肿瘤或病毒感染的个体,在此操作。

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