PHARMACEUTICAL COMPOSITION COMPRISING OSELTAMIVIR PHOSPHATE AND PROCESS OF PREPARATION THEREOF

摘要

This invention in general relates to a pharmaceutical composition of Qseltamivir or its pharmaceutically acceptable salts, esters, solvates, polymorphs, enantiomers or mixtures thereof. In particular, the present invention proposes a stable pharmaceutical composition for constitution into solution or suspension comprising Oseltamivir or its pharmaceutical ly acceptable salts, esters, solvates, polymorphs, enantiomers or mixtures thereof and process for preparing the same. The prior art discloses various technical challenges associated with the preparation of oseltamivir powder for reconstitution with suitable composition attributes such as free of discoloration. The present invention provides a composition of oseltamivir with desirable attributes such as pH5 viscosity and dissolution and is free of discoloration.