NOVEL PHENOLIC COMPOUNDS FROM NERIUM INDICUM WITH ANTI - BREAST CANCER ACTIVITY

摘要

The present invention relates a novel and efficient process for the isolation of two novel phenolic compound I N-(4-Hydroxy-phenyl)- 2-methoxy-2-phenyl-acetamide with a molecular formula CisHisNCb.and compound II N-(4-Hydroxy-phenyl)-2-phenyl-N- phenylacetyl-acetamide with a molecular formula C22H19NO3. The therapeutic efficacy of the novel compounds were assessed over human breast cancer cell lines (MCF-7) and results represented significant cytotoxicity confirming the process of induced apoptosis.