PROCESS FOR THE PREPARATION OF LANTHANUM CARBONATE DIHYDRATE

摘要

Present invention relates to a process for the preparation and pharmaceutical usage of dihydrate form of lanthanum carbonate. Present process produces lanthanum carbonate dihydrate (La2(C03)3.2H20) free of lanthanum hydroxycarbonate and is stable at ambient condition. Lanthanum carbonate dihydrate exhibit improved performance over standard lanthanum carbonate tetrahydrate in phosphate binding studies. Lanthanum carbonate dihydrate is useful for the treatment of hyperphosphataemia in patients with renal failure.[IN-CHE-2009-01121A]