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IMMEDIATE-RELEASE TABLETS CONTAINING A DRUG AND PROCESSES FOR FORMING THE TABLETS.

机译:包含药物的速释片剂和形成片剂的方法。

摘要

The present disclosure relates generally to rapid-release pharmaceutical dosage unit tablets containing a drug that is an inhibitor of the mitogen-activated protein kinase enzyme, a filler and a disintegrant, and to processes for forming the tablets. More specifically, the present disclosure relates to pharmaceutical dosage unit tablets containing cobimetinib, a least one filler, at least one lubricant and at least one disintegrant, and to methods for preparing the tablets from granules formed by dry granulation.
机译:本公开总体上涉及包含药物的速释药物剂量单位片剂,所述药物是促分裂原活化蛋白激酶酶的抑制剂,填充剂和崩解剂,并且涉及形成片剂的方法。更具体地,本公开涉及含有cobimetinib,至少一种填充剂,至少一种润滑剂和至少一种崩解剂的药物剂量单位片剂,并且涉及由通过干法制粒形成的颗粒制备片剂的方法。

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