Graft of Gram-positive Bacillus subtillis, recombinant spores, immunogenic composition, oral vaccine and its application against the influenza A virus

摘要

revealed gram positive bacillus strain chicks subtillis, which contains the recombinant przetrwalnikami selected from the group comprising btl21 (cotb - m2eh - a - s - h), btl22 (cotz - m2eh - a - s - h), btl25 (cgea - m2eh - a - s - h) capable of producing immunogennej response against influenza virus type and.in addition, the subject invention are recombinant spores of strain of gram positive bacillus subtillis babes, immunogenic composition for inducing immune response in the human body against the influenza virus and vaccine and its application to immunisation against wiruso wi influenza type a.