METHOD OF DEPOSITION OF BIOMIMETIC PROTEIN FOR OSTEOINTEGRATIVE BIOFUNCTIONALIZATION OF THE SURFACE OF A NEW ALLOY TI-15TA-5ZR

摘要

The invention relates to a method of deposition of a biomimetic protein onto the surface of an alloy, employed for preparing implants of enhanced capacity of integration into the human bone. According to the invention, the method consists in coating an implant alloy of the type Ti-15Ta-5Zr with 2 g/l BSA protein, i.e. bovine serum albumin, dissolved in the physiological solution Ringer having a pH of 7.4, as a deposition medium, at a temperature of 37°C, for 144 h, to result in a dense uniform coat of high roughness, which contains Ca and P as bioactive elements.