首页> 外国专利> Nucleic acid, polypeptide, expression vector and host cell; osteoprotegerin binding protein and process for its preparation, antibody and medicament for preventing or treating bone diseases

Nucleic acid, polypeptide, expression vector and host cell; osteoprotegerin binding protein and process for its preparation, antibody and medicament for preventing or treating bone diseases

机译:核酸,多肽,表达载体和宿主细胞;骨保护素结合蛋白及其制备方法,用于预防或治疗骨疾病的抗体和药物

摘要

The invention relates to osteoprotegerin binding protein (OPGbp) and related nucleic acids, expression vectors, host cells, processes for preparing said protein by cultivating host cells transformed or transfected with said nucleic acid, antibodies against the protein, methods for detecting the presence of the protein in abiological sample, methods of assessing the ability of atest compound to bind to the protein, and use of antibodies against the protein for preventing or treating bone diseases.
机译:本发明涉及骨保护素结合蛋白(OPGbp)和相关的核酸,表达载体,宿主细胞,通过培养用所述核酸转化或转染的宿主细胞制备所述蛋白的方法,针对该蛋白的抗体,检测其存在的方法。生物样品中的蛋白质,评估待测化合物结合蛋白质的能力的方法以及针对该蛋白质的抗体在预防或治疗骨疾病中的用途。

著录项

  • 公开/公告号SK288559B6

    专利类型

  • 公开/公告日2018-05-02

    原文格式PDF

  • 申请/专利权人 AMGEN INC.;

    申请/专利号SK19990001419

  • 发明设计人 BOYLE WILLIAM J.;

    申请日1998-04-15

  • 分类号C07K14/705;G01N33/53;A61K31/70;A61K31/7088;A61K38;A61K38/17;A61K39;A61K39/395;A61K48;A61P3/14;A61P19;A61P19/02;A61P19/08;A61P19/10;C07K16/28;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12N15/11;C12N15/12;C12P21/08;G01N33/50;G01N33/566;G01N33/577;G01N33/68;

  • 国家 SK

  • 入库时间 2022-08-21 12:50:07

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