首页> 外国专利> PREPARATION OF A MEDICINAL PRODUCT TO PREVENT PREMATURE AGING IN HUMANS, PHARMACEUTICAL COMPOSITION AND COMPOSITE SELECTION METHOD BASED ON THE USE OF NFKbiz SYRNA

PREPARATION OF A MEDICINAL PRODUCT TO PREVENT PREMATURE AGING IN HUMANS, PHARMACEUTICAL COMPOSITION AND COMPOSITE SELECTION METHOD BASED ON THE USE OF NFKbiz SYRNA

机译:基于NFKbiz SYRNA的防止人为过早老化的医药产品的制备,药物成分和成分选择方法

摘要

Preparation of a drug to prevent premature aging in humans, pharmaceutical composition and method of compound selection based on the use of NFKbiz siRNA. Use of a composition comprising RNA molecules for the manufacture of a medicament to prevent premature aging in a human and pharmaceutical composition. Method of selecting compounds useful in the treatment of premature aging, which includes incubating renal tubular cells, determining whether the expression of NFKbiz in renal tubular cells is less than the expression of NFKbiz in a control sample and identifying a compound as a compound useful in The treatment of premature aging.
机译:基于NFKbiz siRNA的用途的药物制备,防止人过早衰老的药物组合物和化合物选择方法。包含RNA分子的组合物在制备用于防止人和药物组合物中过早衰老的药物中的用途。选择可用于治疗过早衰老的化合物的方法,该方法包括孵育肾小管细胞,确定肾小管细胞中NFKbiz的表达是否低于对照样品中NFKbiz的表达以及鉴定化合物作为可用于治疗早衰的化合物。治疗早衰。

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