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Activin-actrii antagonists and uses for the treatment of bone disorders and other disorders
Activin-actrii antagonists and uses for the treatment of bone disorders and other disorders
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机译：Activin-actrii拮抗剂及其在治疗骨疾病和其他疾病中的用途
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摘要
An ActRII inhibitor for use in a method for the treatment of vascular calcification in a subject, wherein said ActRII inhibitor is a polypeptide comprising an amino acid sequence selected from the group consisting of: a) 90% identical to SEQ ID NO: 2; b) 95% identical to SEQ ID NO: 2; c) 98% identical to SEQ ID NO: 2; d) SEQ ID NO: 2; e) 90% identical to SEQ ID NO: 3; f) 95% identical to SEQ ID NO: 3; g) 98% identical to SEQ ID NO: 3; h) SEQ ID NO: 3; i) 90% identical to SEQ ID NO: 6; j) 95% identical to SEQ ID NO: 6; k) 98% identical to SEQ ID NO: 6; 1) SEQ ID NO: 6; m) 90% identical to SEQ ID NO: 7; n) 95% identical to SEQ ID NO: 7; o) 98% identical to SEQ ID NO: 7; p) SEQ ID NO: 7; q) 90% identical to SEQ ID NO: 12; r) 95% identical to SEQ ID NO: 12; s) 98% identical to SEQ ID NO: 12; ...
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机译：用于治疗对象的血管钙化的方法中的ActRII抑制剂，其中所述ActRII抑制剂是包含选自以下的氨基酸序列的多肽：a）与SEQ ID NO：2相同的90％;和b）与SEQ ID NO：2 95％相同; c）与SEQ ID NO：2 98％相同; d）SEQ ID NO：2; e）与SEQ ID NO：3 90％相同; f）与SEQ ID NO：3 95％相同; g）与SEQ ID NO：3 98％相同; h）SEQ ID NO：3; i）与SEQ ID NO：6 90％相同; j）与SEQ ID NO：6 95％相同; k）与SEQ ID NO：6的98％相同; 1）SEQ ID NO：6; m）与SEQ ID NO：7 90％相同; n）与SEQ ID NO：7 95％相同; o）与SEQ ID NO：7 98％相同; p）SEQ ID NO：7; q）与SEQ ID NO：12 90％相同; r）与SEQ ID NO：12 95％相同; s）与SEQ ID NO：12 98％相同; ...
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