Propylene glycol solvate of (2s, 3r, 4s, 5s, 6r) -2- 4-chloro-3- (4-ethoxy-benzyl) -phenyl -6-hydroxymethyl-2-methoxy-tetrahydro-pyran-3, 4,5-triol as an SGT2 inhibitor for the treatment of diabetes

摘要

A pharmaceutical composition comprising a pharmaceutically acceptable carrier or diluent and a crystalline structure of a compound of formula I ** (See formula) ** in the form of its propylene glycol solvate for use in the treatment of a selected disorder of diabetes, retinopathy diabetes, diabetic neuropathy, diabetic nephropathy, delayed scarring, insulin resistance, hyperglycemia, hyperinsulinemia, elevated levels of fatty acids or glycerol in the blood, hyperlipidemia, dyslipidemia, obesity, hypertriglyceridemia, Syndrome X, diabetic complications, atherosclerosis or hypertension, or the use in increasing the levels of high density lipoproteins in a mammal.