Early treatment and prevention of increased muscle tone

摘要

Botulinum toxin for use in a method to prevent inappropriate neuronal plasticity, comprising the step of administering a therapeutically effective amount of a botulinum toxin to at least a portion of a 1A sensory afferent of at least one muscle before the onset of spasticity and / or before inappropriate neuronal plasticity becomes clinically evident and in which said administration prevents or attenuates the development of said inappropriate neuronal plasticity.