Identification of CD8 + T cells that are CD161 hi and / or IL-18R (alpha) hi and have a rapid drug evacuation capacity

摘要

An isolated population of long-lasting memory human CD8 + T cells that have high surface expression of CD161 and IL-18Rα, where the population (a) proliferates in response to IL-7, IL-15 or both, ( b) rapidly evacuates Rh123 and (c) comprises central memory T cells and / or effector memory T cells.