首页> 外国专利> Method for preparing an external surface of a planar waveguide capable of Uniting Target samples along a Plurality of Predetermined lines and a planar waveguide

Method for preparing an external surface of a planar waveguide capable of Uniting Target samples along a Plurality of Predetermined lines and a planar waveguide

机译:制备能够沿着预定线将目标样本结合在一起的平面波导的外表面的方法和平面波导

摘要

Method for preparing an external surface (11) of a planar waveguide (1) that is capable of linking Target samples along a Plurality of Predetermined Lines (4),Default still prepared Lines (4), so in operationAn evanescent Field of Coherent Light coupled and spread through the planar waveguide (1) Dispersing in target samples along the Plurality of Predetermined Lines (4) RNterferir Constructively in a Predetermined location detection with a difference in Optical Path length that is an integer multiple of the Wavelength of the Coherent light is proPaid through the planar waveguide, or when the Predetermined Lines (4) arranged such that in operation,The evanescent Field of the Coherent Light coupled and spread through the planar waveguide (1) Dispersing in target samples arranged along lines of the Plurality of Predetermined.(4) to interfere in predetermined directions within the planar waveguide (1),Understanding the stages of the procedure: - to provide a planar waveguide (1) which has an external surface (11) suitable for the accession of a Molecule linking the product (2)(11); and external Applied sequentially to a Plurality of enlazadoras molecules (2, 5, 2) The Outer Surface (11),Assembling a Plurality of at least a Plurality of Molecules enlazadoras (2, 5; 2) to form a single layer of Molecules enlazadoras (25; 2) with individual layers that are formed on top of one another from the external surface (11) of the planar waveguide (1), (2, Understanding each Molecule Linking5; 2) a functional Group (22, 52; 22) and a group of Head (21, 51; 21), the Head Group (21,51; 21) being capable of adhering to the Outer Surface (11) of the planar waveguide (1) or Functional groups (22) of the previous layer of Molecules enlazadoras (2),And in which Functional groups (52; 22 (5) of the enlazadoras molecules; 2) the top layer are connected to the Protecting groups fotolu00e1biles (3) so that each Functional Group (52; 22 (d)And the Upper Layer attached to said Group fotolu00e1bil protector (3) is incapable of binding to a complementary Functional Group of a Molecule to expose these additional Protective groups; and (3) fotolu00e1bilesThe top layer disposed along the Plurality of Predetermined Lines (4) in the light of a Predetermined Wavelength to remove the Protecting groups fotolu00e1biles exposed (3) dAnd the functional groups (52; 22) capable of binding to a complementary additional Functional Group of a Molecule.
机译:制备平面波导(1)的外表面(11)的方法,该平面波导可以沿着预定的线(4),默认的仍然准备的线(4)链接多个目标样本,因此在操作中耦合了相干光的e逝场并通过平面波导传播(1)沿预定线的多个散布在目标样品中(4)RNterferir在预定位置检测中以有建设性的方式进行预定,光程长度的差是相干光波长的整数倍通过平面波导,或者当预定线(4)布置为在工作中时,相干光的van逝场耦合并通过平面波导(1)传播,分散在沿多个预定线排列的目标样品中。 4)在平面波导(1)内的预定方向上进行干涉,了解该过程的步骤:-提供具有以下特征的平面波导(1):外表面(11),适于连接连接产物(2)(11)的分子;将外部和外部依次应用于多个enlazadoras分子(2、5、2)外表面(11),组装至少多个Molacules enlazadoras(2、5; 2)的多个分子以形成单层的Enlazadoras分子(25; 2)具有从平面波导(1)的外表面(11)彼此层叠形成的单独层,(2,理解每个分子连接5; 2)官能团(22、52; 22) )和一组头部(21、51; 21),该头部组(21,51; 21)能够粘附到平面波导(1)的外表面(11)或该模块的功能组(22)分子enlazadoras的上一层(2),其中enlazadoras分子的官能团(52; 22(5); 2)的顶层与保护基团(3)连接,因此每个官能团(52) ; 22(d),附着在所述组摄影保护剂(3)上的上层不能与分子的互补官能团结合,从而与暴露这些额外的保护基团;和(3)摄像头根据预定波长沿着预定线(4)的多个设置顶层,以去除暴露的保护基摄像头(3)d和能够结合的官能团(52; 22)互补的分子附加官能团。

著录项

  • 公开/公告号ES2671951T3

    专利类型

  • 公开/公告日2018-06-11

    原文格式PDF

  • 申请/专利权人 F. HOFFMANN-LA ROCHE AG;

    申请/专利号ES20140701322T

  • 发明设计人 FATTINGER CHRISTOF;

    申请日2014-01-17

  • 分类号G01N33/543;

  • 国家 ES

  • 入库时间 2022-08-21 12:48:32

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