HEMODIALYSIS AND PERITONEAL DIALYSIS SOLUTIONS COMPRISING ONE OR MORE CREATINE COMPOUNDS

摘要

The present invention relates to a haemodialysis solution or concentratethereof comprising creatine compound(s)and the use of creatine compound(s) for preparing a dialysis solution orconcentrate thereof. Furthermore, the present invention isdirected to a method for preparing creatine-containing dialysis solutions andconcentrates. In addition, the present invention is directedto a method for treating patients with dialysis dependent renal failure withcreatine compounds and to provide a variety ofsignificant health benefits and improvement of life quality parameters fordialysis patients. This is achieve by supporting and improvingthe physiological functions of the patients organs and cells via creatinecompounds delivery to the patients, and by protectingorgans and cells (specifically including blood cells) of these patients fromdeleterious effects of a variety of endogenous orexogenous cellular stressors that are linked to the disease state or to theclinical treatment modalities. Furthermore in peritonealdialysis solutions creatine can be used as an osmotic agent preventing sideeffects caused by high glucose supplementation.