METHODS AND COMPOSITIONS FOR TREATING ATTENTION DEFICIT HYPERACTIVITY DISORDER, ANXIETY AND INSOMNIA USING DEXMEDETOMIDINE TRANSDERMAL COMPOSITIONS

摘要

The invention provides devices, kits and approaches for treating AttentionDeficitHyperactivity Disorder (ADHD), anxiety or insomnia, comprising a compositionof the .alpha.2-adrenergicagonist, dexmedetomidine. Clinically, dexmedetomidine is used as a sedativeand is parenterally, intravenously or orally administered, thus requiringclose supervisionby healthcare professionals. Provided herein are select embodiments oftransdermaldelivery devices that are configured to maintain contact with a subject andcomprisedexmedetomidine compositions that are formulated in a manner sufficient todeliver anamount of dexmedetomidine to the skin surface of the subject for treatingADHD, anxietyor insomnia.