METHOD FOR PRODUCING AFFINITY SEPARATION MATRIX, AND AFFINITY SEPARATION MATRIX

摘要

The purpose of the present invention is to provide an affinity separation matrix having extremely excellent binding capacity and binding efficiency with respect to a κ-chain variable region-containing peptide, a method for producing the affinity separation matrix, and a method for producing a κ-chain variable region-containing peptide using the affinity separation matrix. The affinity separation matrix production method according to the present invention is characterized by including a step for immobilizing, as a ligand, a κ-chain variable region-containing peptide having a cysteine residue at the N-terminus and/or the C-terminus thereof to a water-insoluble carrier with the terminal cysteine residue being interposed therebetween.