CRYSTALLINE POLYMORPH OF 15Β-HYDROXY-OSATERONE ACETATE

摘要

Provided is a crystalline polymorph A of 15β-hydroxy-osaterone acetate having improved stabilities (storage stability, pulverization stability, and absorption property). Diffraction peaks characteristic of this crystalline polymorph A of 15β-hydroxy-osaterone acetate, in a powder X-ray diffraction spectrum, appear at diffraction angles 2θ of 9.6°±0.2°, 17.1°±0.2°, and 20.2°±0.2°. The crystalline polymorph A has a melting point of 280-283°C, and is a prismatic crystal.