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METHODS FOR PREDICTING RISK OF RECURRENCE AND/OR METASTASIS IN SOFT TISSUE SARCOMA

机译:预测软组织肉瘤复发和/或转移风险的方法

摘要

The disclosure related to the development of a gene expression profile to predict soft tissue sarcoma (STS) recurrence, distant metastasis, or both. Analyses identified a 36-gene gene expression profile able to accurately predict risk in a cohort of soft tissue sarcoma tumors independent of histologic and pathologic grade. This discovery offers an opportunity to enhance current staging of STS to identify patients who have a higher risk of recurring, distant metastasis, or both.
机译:本公开涉及预测软组织肉瘤(STS)复发,远处转移或两者的基因表达谱的发展。分析确定了36个基因的基因表达谱,能够准确预测一组软组织肉瘤肿瘤的风险,而与组织学和病理学分级无关。该发现为增强当前STS分期提供了机会,以识别复发,远处转移或两者均具有较高风险的患者。

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