首页> 外国专利> Dicarboxylic acid bisamide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing dicarboxylic acid bisamide derivatives

Dicarboxylic acid bisamide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing dicarboxylic acid bisamide derivatives

机译:二羧酸双酰胺衍生物,其用途,基于其的药物组合物和生产二羧酸双酰胺衍生物的方法

摘要

The present invention relates to novel biologically active compounds being dicarboxylic acid bisamide derivatives of general formula (I), or pharmaceutically acceptable salts thereof, which are capable of complexing or chelating metal ions, and the use thereof as an agent for the prevention and/or treatment of cardiovascular, viral, cancerous, neurodegenerative and inflammatory diseases, diabetes and age-related diseases as well as diseases caused by microbial toxins, and also alcoholism, alcoholic cirrhosis, anaemia, porphyria cutanea tarda and transition metal salt poisoning. The present invention also relates to novel methods for producing dicarboxylic acid bisamide derivatives of general formula (I).
机译:本发明涉及新颖的生物活性化合物,其为通式(I)的二羧酸双酰胺衍生物或其药学上可接受的盐,其能够络合或螯合金属离子,及其作为预防和/或治疗剂的用途。治疗心血管,病毒,癌症,神经退行性和炎性疾病,糖尿病和与年龄有关的疾病,以及由微生物毒素引起的疾病,以及酗酒,酒精性肝硬化,贫血,皮肤红斑卟啉和过渡金属盐中毒。本发明还涉及制备通式(I)的二羧酸双酰胺衍生物的新方法。

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