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BIOMARKER COMPOSITION FOR DETECTION OF ENDOMETRIOSIS AND APPLICATION THEREOF

机译:用于检测子宫内膜异位的生物标志物组合物及其应用

摘要

A biomarker composition for detection or risk assessment of endometriosis, and application thereof. The biomarker composition comprises at least one of 24 nucleic acids. The 24 nucleic acids have sequences represented by Seq ID No. 1 to Seq ID No. 24 respectively, or sequences having similarity of 97% or more to those represented by Seq ID No. 1 to Seq ID No. 24. The biomarker composition has excellent specificity, and can be used for early diagnosis of endometriosis, thereby providing a new approach for detection or risk assessment of endometriosis. The biomarker composition has high sensitivity and specificity, good reproducibility, and important application value. By using a genital tract specimen as a biomarker detection specimen, the material is easily available, the operation steps are simple, and continuous in-vitro detection can be implemented.
机译:用于子宫内膜异位症的检测或风险评估的生物标志物组合物及其应用。生物标志物组合物包含24种核酸中的至少一种。这24个核酸分别具有由Seq ID No.1至Seq ID No.24表示的序列,或与由Seq ID No.1至Seq ID No.24表示的序列具有97%或更高的相似性的序列。优良的特异性,可用于子宫内膜异位症的早期诊断,从而为检测子宫内膜异位症或风险评估提供了一种新方法。该生物标志物组合物具有高灵敏度和特异性,良好的可重复性,并具有重要的应用价值。通过将生殖道标本用作生物标志物检测标本,该材料易于获得,操作步骤简单,并且可以实现连续的体外检测。

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