METHOD FOR POSITRON EMISSION TOMOGRAPHY (PET) IMAGING ANALYSIS FOR CLASSIFYING AND DIAGNOSING OF NEUROLOGICAL DISEASES

摘要

A method of using PET imaging includes using PET images obtained using a radiotracer for the determination of the progressive course of regional brain PET activities for a progressive neurodegenerative disease (e.g., MCI, AD, and CTE). The method may be used for the automatic staging of neurodegenerative disease for a particular patient/subject based on regional intensity and spatial patterns of the brain signals measured by PET imaging. The method may also be used to diagnose or classify the disease of a patient among multiple possibilities based on PET imaging profiles (e.g., for separating or distinguishing CTE from AD).