首页> 外国专利> COMPOUND FOR POSITRON EMISSION TOMOGRAPHY IMAGE OF ATHEROSCLEROTIC ARTERIAL PLAQUE, AND METHOD FOR PRODUCING SAME

COMPOUND FOR POSITRON EMISSION TOMOGRAPHY IMAGE OF ATHEROSCLEROTIC ARTERIAL PLAQUE, AND METHOD FOR PRODUCING SAME

机译:动脉粥样硬化斑块的正电子发射断层扫描图像的化合物及其生产方法

摘要

The present invention relates to a compound marked with a radioactive isotope used for positron emission tomography (PET) for imaging atherosclerotic arterial plaque, which is a cause of cardio-cerebrovascular diseases; and a production method and an application thereof. More specifically, the present invention relates to a compound, a method for producing the same, and a method for imaging atherosclerotic arterial plaque by using the same, wherein the compound is marked by a radioactive isotope and coupled with 2 to 4 peptides capable of selectively targeting atherosclerotic arterial plaque, and thus an excellent PET image of atherosclerotic plaque in an artery that has a fast flow of blood can be obtained in a short amount of time using a small amount of the compound.
机译:本发明涉及一种标记有放射性同位素的化合物,该化合物用于正电子发射断层扫描(PET),以对引起心血管疾病的动脉粥样硬化斑块进行成像。及其生产方法和应用。更具体地,本发明涉及一种化合物,其制备方法以及通过使用该化合物对动脉粥样硬化斑块进行成像的方法,其中该化合物以放射性同位素标记并且与2至4个能够选择性地结合的肽偶联。以少量的化合物为靶标,可以在短时间内获得具有快速血液流动的动脉中动脉粥样硬化斑块的良好PET图像。

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