首页> 外国专利> COMPOSITION FOR PREVENTING, ALLEVIATING OR TREATING ARTHRITIS, CONTAINING EXTRACT OF MOLLUGO PENTAPHYLLA AS ACTIVE INGREDIENT

COMPOSITION FOR PREVENTING, ALLEVIATING OR TREATING ARTHRITIS, CONTAINING EXTRACT OF MOLLUGO PENTAPHYLLA AS ACTIVE INGREDIENT

机译：预防，减轻或治疗关节炎的成分，含有五味子五加的提取物作为有效成分

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摘要

The present invention relates to a composition for preventing, alleviating or treating arthritis, containing an extract of Mollugo pentaphylla as an active ingredient. More specifically, the Mollugo pentaphylla extract of the present invention is not cytotoxic, has an effect of inhibiting the generation of NO, induced by inflammation, and the increase in TNFα, PGE₂, and IL-6, reduces the IL-1β amount increased because of gouty arthritis, relieves pain caused by osteoarthritis, and reduces the amount of inflammatory cytokines, thereby being usable in the prevention, alleviation or treatment of arthritis. 展开▼

机译：本发明涉及一种预防，减轻或治疗关节炎的组合物，该组合物含有五叶草薄荷提取物作为活性成分。更具体地，本发明的五叶草提取物没有细胞毒性，具有抑制由炎症引起的NO的产生以及TNFα，PGE _{2
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公开/公告号WO2018080054A1

专利类型

公开/公告日2018-05-03

原文格式PDF

申请/专利权人 KOREA INSTITUTE OF ORIENTAL MEDICINE;
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申请/专利号WO2017KR11224

发明设计人 KIM DONG SEON;LEE YUN MI;SON EUN JUNG;KIM OHN SOON;LEE YOUNG-SIL;
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申请日2017-10-12

分类号A23L33/105;A61K36/36;

国家 WO

入库时间 2022-08-21 12:44:18

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1. 含有益智提取物作为有效成分的用于预防、改善或治疗骨关节炎的组合物 [P] . 中国专利： CN111093398A . 2020-05-01

2. 含有以单乙酰基二酰基甘油化合物作为有效成分的类风湿性关节炎的预防或者治疗用组合物 [P] . 中国专利： CN108420812A . 2018-08-21

3. COMPOSITION FOR PREVENTING, IMPROVING OR TREATING OF T H2-MEDIATED IMMUNE DISEASE COMPRISING EXTRACTS FROM MOLLUGO PENTAPHYLLA, EXTRACTS FROM ALISMA PLANTAGO-AQUATICA, EXTRACTS FROM EAEOCARPUS SYLVESTRIS OR EXTRACTS FROM CIMICIFUGA ACERINA [P] . 韩国专利： KR20160001805A . 2016-01-07

机译：用于预防，改善或治疗由Mollugo Pentaphylla提取物，来自ALISMA PLANTAGO-Aquatica的提取物，来自EAEOCARPUS SYLVESTRIS的提取物或来自小叶蝉的提取物的T H2介导的免疫疾病的组合物

4. COMPOSITION FOR ALLEVIATING, PREVENTING OR TREATING ARTHRITIS, CONTAINING STEWARTIA PSEUDOCAMELLIA LEAF EXTRACT AND MACLURA TRICUSPIDATA LEAF EXTRACT AS ACTIVE INGREDIENTS [P] . 世界知识产权组织专利： WO2020218733A2 . 2020-10-29

机译：包含，预防，治疗或治疗关节炎，含有StewaRTIa PSEUDOCAMELLIA叶提取物和MACLURA TRICUSPIDATA叶提取物作为有效成分的组合物

5. Composition for prevention improvement or treatment of arthritis comprising Mollugo pentaphylla extract as effective component [P] . 韩国专利： KR101863603B1 . 2018-06-04

机译：预防或治疗关节炎的组合物，其包含五叶薄荷提取物作为有效成分

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10. Poster session 2Morphogenetic mechanisms290MiR-133 regulates retinoic acid pathway during early cardiac chamber specification291Bmp2 regulates atrial differentiation through miR-130 during early heart looping formationDevelopmental genetics294Association of deletion allele of insertion/deletion polymorphism in alpha 2B adrenoceptor gene and hypertension with or without type 2 diabetes mellitus295Association of G1359A polymorphism of the endocannabinoid type 1 receptor (CNR1) with coronary artery disease (CAD) with type 2 diabetes mellitusCell growth, differentiation and stem cells - Vascular298Gamma-secretase inhibitor prevents proliferation and migration of ductus arteriosus smooth muscle cells: a role of Notch signaling in postnatal closure of ductus arteriosus299Mesenchymal stromal-like cells (MLCs) derived from induced pluripotent stem (iPS) cells: a promising therapeutic option to promote neovascularization300Sonic Hedgehog promotes mesenchymal stem cell differentiation to vascular smooth muscle cells in cardiovacsular disease301Proinflammatory cytokine secretion and epigenetic modification in endothelial cells treated LPS-GinfivalisCell death and apoptosis - 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focus on the nitric oxide pathwayAging395Heart failure with preserved ejection fraction develops when feeding western diet to senescence-accelerated mice396Cardiovascular markers as predictors of cognitive decline in elderly hypertensive patients397Changes in connexin43 in old rats with volume overload chronic heart failureGenetics and epigenetics400Calcium content in the aortic valve is associated with 1G>2G matrix metalloproteinase 1 polymorphism401Neuropeptide receptor gene s (NPSR1) polymorphism and sleep disturbances402Endothelin-1 gene Lys198Asn polymorphism in men with essential hypertension complicated and uncomplicated with chronic heart failure403Association of common polymorphisms of the lipoprotein lipase and pon1 genes with the metabolic syndrome in a sample of community participantsGenomics, proteomics, metabolomics, lipidomics and glycomics405Gene expression quantification using multiplexed color-coded probe pairs to determine RNA content in sporadic cardiac myxoma406Large-scale phosphorylation study of the type 2 diabetic heart subjected to ischemia / reperfusion injury407Transcriptome-based identification of new anti-inflammatory properties of the olive oil hydroxytyrosol in vascular endothelial cell under basal and proinflammatory conditions408Gene polymorphisms combinations and risk of myocardial infarctionComputer modelling, bioinformatics and big data411Comparison of the repolarization reserve in three state-of-the-art models of the human ventricular action potentialMetabolism, diabetes mellitus and obesity414Endothelial monocyte-activating polypeptide-II improves heart function in type -I Diabetes mellitus415Admission glucose level is independent predictor of impaired left ventricular function in patients with acute myocardial infarction: a two dimensional speckle-tracking echocardiography study416Association between biochemical markers of lipid profile and inflammatory reaction and stiffness of the vascular wall in hypertensive patients with abdominal obesity417Multiple common co-morbidities produce left ventricular diastolic dysfunction associated with coronary microvascular dysfunction, oxidative stress and myocardial stiffening418Investigating the cardiovascular effects of antiretroviral drugs in a lean and high fat/sucrose diet rat model of obesity419Statins in the treatment of non-alcoholic steatohepatitis (NASH). 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