首页> 外国专利> ANTIMICROBIAL PEPTIDE ANALOG DERIVED FROM HALIOTIS DISCUS AND ANTIMICROBIAL PHARMACEUTICAL COMPOSITION CONTAINING SAME

ANTIMICROBIAL PEPTIDE ANALOG DERIVED FROM HALIOTIS DISCUS AND ANTIMICROBIAL PHARMACEUTICAL COMPOSITION CONTAINING SAME

机译：盘状葡萄球菌的抗菌肽类似物和包含相同成分的抗菌药物成分

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摘要

The present invention relates to an antimicrobial peptide analog derived from Haliotis discus and an antimicrobial pharmaceutical composition containing same. The antimicrobial peptide analog, according to the present invention, is designed with hdMolluscidin, which is a peptide derived from the gills of Haliotis discus and is designed to allow commercialization by reducing the number of amino acids. Also, the antimicrobial peptide analog has excellent antimicrobial activity despite reduced amino acids. In addition, the antimicrobial peptide analog has low membrane permeability and low hemolytic activity.

机译：本发明涉及衍生自铁线虫（Haliotis discus）的抗微生物肽类似物和包含其的抗微生物药物组合物。根据本发明，抗微生物肽类似物用hdMolluscidin设计，hdMolluscidin是衍生自 Haliotis discus ill的肽，并被设计为通过减少氨基酸数量来实现商业化。而且，尽管氨基酸减少，但抗菌肽类似物仍具有优异的抗菌活性。另外，抗微生物肽类似物具有低的膜渗透性和低的溶血活性。 展开▼

著录项

公开/公告号WO2018092955A1

专利类型

公开/公告日2018-05-24

原文格式PDF

申请/专利权人 INDUSTRY-ACADEMIC COOPERATION FOUNDATION KUNSAN NATIONAL UNIVERSITY;
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申请/专利号WO2016KR13413

发明设计人 SEO JUNG-KIL;LEE KI-YOUNG;CHO SANG-MAN;LEE IN-AH;
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申请日2016-11-21

分类号C07K7/06;C07K7/08;A61K8/64;A61K38/08;A61K38/10;A61Q19;A23L33/18;A23K20/147;A23K20/195;

国家 WO

入库时间 2022-08-21 12:44:04

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