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IMPROVED METHODS OF TREATING LUNG CANCER BY PREDICTING RESPONDERS TO CISPLATIN-PEMETREXED COMBINATION THERAPY
IMPROVED METHODS OF TREATING LUNG CANCER BY PREDICTING RESPONDERS TO CISPLATIN-PEMETREXED COMBINATION THERAPY
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机译:通过预测对人参皂甙联合疗法的肺癌治疗方法的改进
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摘要
Methods are provided for identifying whether a lung tumor will be responsive to treatment with the combination of the therapeutic agents cisplatin and pemetrexed. Specified ERCC1, TS, p16, and FRα fragment peptides are precisely detected and quantitated by SRM-mass spectrometry directly in lung tumor cells collected from lung tumor tissue that was obtained from a cancer patient and compared to reference levels in order to determine if the lung cancer patient will positively respond to treatment with the combination of cisplatin and pemetrexed therapeutic agents.
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