Provided are applications of Collinsella shenzhenensis in treating and/or preventing inflammation-related diseases and cardiovascular diseases. Also provided are a composition used for treating and/or preventing the inflammation-related diseases and cardiovascular diseases, comprising drugs, beverages, foods or animal feed compositions, and a method for alleviating the diseases of intestinal tracts of mammals, decreasing blood fat of the mammals, control the reduction of the weights of the of the mammals and/or decreasing disease activity indexes of the mammals.
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