首页> 外国专利> NATURAL KILLER CELL EXPRESSING ANTI-COTININE CHIMERIC ANTIGEN RECEPTOR

NATURAL KILLER CELL EXPRESSING ANTI-COTININE CHIMERIC ANTIGEN RECEPTOR

机译:表达抗可替宁嵌合抗原受体的天然杀伤细胞

摘要

The present invention relates to a natural killer cell expressing an anti-cotinine chimeric antigen receptor (CAR) specifically binding to cotinine, and a cell therapeutic agent comprising same. The natural killer cell expressing a chimeric antigen receptor specifically binding to cotinine, according to the present invention, can effectively move to tumor tissue, regardless of the kind of cancer, depending on the binding substance bound to cotinine. Therefore, the natural killer cell according to the present invention can be usefully employed as a gene therapy exhibiting a highly efficient anticancer effect.
机译:本发明涉及表达特异性结合可替宁的抗可卡因嵌合抗原受体(CAR)的自然杀伤细胞,以及包含该杀伤剂的细胞治疗剂。根据本发明,表达特异性结合可替宁的嵌合抗原受体的天然杀伤细胞可以有效地向肿瘤组织移动,而与癌症的种类无关,这取决于与可替宁结合的结合物质。因此,根据本发明的天然杀伤细胞可以有效地用作表现出高效抗癌作用的基因治疗。

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