NOVEL THERAPEUTIC AGENT FOR NEPHROGENIC ANEMIA TARGETING ERYTHROPOIETIN RECEPTOR VIA NO AND NO-pathway STIMULATION

摘要

Provided is a novel therapeutic agent for nephrogenic anemia which is efficacious for ESA resistant patients too. A medicinal composition which comprises an organic nitrate and a pharmacologically acceptable carrier; and a therapeutic agent for nephrogenic anemia which comprises a therapeutically effective amount of an organic nitrate. As the organic nitrate, isosorbide nitrate or isosorbide mononitrate is preferred.