NUCLEIC ACID DRUG CAPABLE OF INHIBITING INVASION AND METASTASIS OF CANCER, AND CANCER BIOMARKER

摘要

Disclosed is an anti-tumor agent comprising a SNORA23 gene expression inhibitor. The SNORA23 expression inhibitor may be an oligonucleotide containing at least one nucleoside structure represented by formula (1) (wherein each of "Base" and "A" represents a specific substituent or structure) or a pharmacologically acceptable salt thereof. Also disclosed is an anti-tumor agent comprising an SYNE2 gene expression inhibitor. Also disclosed is a use of SNORA23 as a biomarker, said use being characterized in that SNORA23 in a blood sample is measured for the purpose of detecting the occurrence of invasion or metastasis of a tumor.