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METHODS FOR DIAGNOSING AND TREATING GASTRIC CANCER USING MIRNA EXPRESSION
METHODS FOR DIAGNOSING AND TREATING GASTRIC CANCER USING MIRNA EXPRESSION
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机译:利用miRNA表达诊断和治疗胃癌的方法
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摘要
Dysregulated expression of microRNAs (miRNAs) has emerged as a hallmark feature in human cancers. Aspects of the disclosure relate to methods for selecting optimal therapy for a patient from several alternative treatment options. A major clinical challenge in cancer treatment is to identify the subset of patients who will benefit from a therapeutic regimen, both in metastatic and adjuvant settings. The number of anti-cancer drugs and multi-drug combinations has increased substantially in the past decade, however, treatments continue to be applied empirically using a trial-and-error approach. Here methods and compositions are provided to determine the optimal treatment option for gastric cancer patients.
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