METHODS OF HIGH-THROUGHPUT MASS SPECTROMETRY BASED URINE TEST FOR COLORECTAL STATES

摘要

Methods for the assessment of colorectal polyps in general, and adenomatous polyps in particular, by mass spectrometry based measurement of metabolites in urine are described. In some embodiments, certain metabolites are identified as being reduced in concentration or quantity in subjects with colorectal polyps as compared with subjects without colorectal polyps. The measurement of these metabolites in urine can indicate the presence of, or predisposition to, colorectal polyps in general, or adenomatous polyps in particular, in a subject.